Volume 67 (2017) Issue: 2017 No#3

IGF1 gene polymorphism in selected species of the Canidae family

Author(s): Jakubczak Andrzej, Gryzinska Magdalena, Horecka Beata, Jezewska-Witkowska Grazyna

Keywords:IGF1, SNP, dog, fox, raccoon dog

The gene IGF1 has been shown to have a significant influence on the size of individuals, including animals of the Canidae family. In this study we determined SNP mutations of the IGF1 gene in dogs, raccoon dogs and farmed and free-living red foxes from Poland and Canada. No SNP mutations were noted in dogs or raccoon dogs, but a total of 14 single nucleotide polymorphisms were identified in foxes, including 12 substitutions, as well as one new mutation missense variant (exon 6) in wild Polish foxes and one synonymous mutation variant in wild foxes from Canada. We identified specific SNP profiles characteristic only for farmed foxes and only for wild foxes, as well as specific SNP profiles or wild foxes from North America (Canada) and from Europe (Poland).