Volume 62 (2012) Issue: 2012 No#4

Reconstruction of the mandible with an autogenous corticocancellous bone graft and fibrin glue: an animal experiment

Author(s): Mirković Z, Lončarević S, Đurđević D, Bubalo Marija, Jović S, Gardašević Milka

Keywords:corticocancellous bone graft, fibrin glue, experimental animals, mandibular reconstruction

This paper reports on an experimental animal study evaluating a method of mandibular reconstruction in dogs using autogenous corticocaneclous bone graft and fibrin glue. Eight animals underwent a resection at the mandibular body and primary reconstruction was carried out using osteosynthesis plates and screws. The defect was bridged with an autogenous particulate bone graft from the anterior iliac crest. To accelerate bone healing, fibrin glue (FG) was mixed with particulate bone graft. The hypothesis of this study was based on the presumption that bone healing, in segmental reconstruction of the dog mandible with a particulate cancellous bone graft mixed with FG, would be successful. All dogs had eventful healing. The histological results were less favorable with regard to bone remodeling than the results obtained in similar experiments with a particulate corticocancellous bone graft.