Volume 60 (2010) Issue: 2010 No#5-6

The new experimental design of arterialized venous flap on the rabbit ear model

Author(s): Lalković M, Kozarski J, Panajotović Lj, Šijan G, Đurđević D, Miković N, Apostolović M, Pavlović M, Gvozdić D

Keywords:arterialized venous flap, new experimental design, rabbit ear

The aim of this study was to test a new experimental design of venous system arterialization on the rabbit ear arterialized venous flap (AVF) model. Total number of 10 "Big Chinchila" rabbits were divided in two experimental groups. On both ears of the five rabbits (Group 1) we have performed our original method of venous system arterialization with microsurgical arterialization of the central artery and vein with the preservation of central and peripheral vascular perfusion; at both ears of five rabbits (Group 2) we have performed AVF according to Byan et al., (1995). Vital AVF surface and necrosis percentage were determined in both experimental groups at day 1 and day 14 and results were compared using Student t-test. The results of our experiment indicate that our new experimental design of the AVF on rabbit ear model has better hemodynamic conditions, improves AVF survival and gives significantly bigger vital flap surface at 14 days after venous system arterialization.