Volume 65 (2015) Issue: 2015 No#1

Nasal transmissible venereal tumor in a jack russel terrier bitch

Author(s): Feghiu Adrian, Crînganu Dan, Dumitrescu Florin, Pascal Manuela, Vasilescu Florina, Militaru Manuella

Keywords:canine transmissible venereal tumor, complex diagnosis, nasal localisation

A two-year old Jack Russell Terrier female with left-sided epistaxis was brought to the Clinic of the Bucharest Faculty of Veterinary Medicine. Endoscopy of the left nasal cavity revealed a cauliflower-like mass. Cytological and histopathological features were specific to canine transmissible venereal tumour (CTVT). Tumor tissue showed positive immunoreactivity to anti-vimentin monoclonal antibody (90%) and Ki67 (35%) and samples were negative for anti-cytokeratin monoclonal antibody. Chemotherapy with vincristine sulphate at a dose of 0.025 mg/kg i.v./week for 6 administrations was successful. This paper presents a primary form of nasal CTVT in a Jack Russell Terrier female.