Volume 65 (2015) Issue: 2015 No#2

Acute phase proteins as markers of infectious diseases in small animals

Author(s): Schmidt Elizabeth Moreira Dos Santos, Eckersall Peter David

Keywords:acute phase proteins; Haptoglobin; C-reactive protein; Serum amyloid A; dogs

During the acute phase response, there is an increased production and release of certain proteins known as acute phase proteins (APPs) which can be produced by hepatocytes and peripheral tissues such as C-reactive protein (CRP), serum amyloid A (SAA), haptoglobin (Hp), alpha-1 acid glycoprotein (AGP). These proteins have been investigated as markers of various infectious diseases in small animals and the purpose of this review is to update the current knowledge about APPs in infectious diseases in dogs and cats.